High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.

Research output: Contribution to journalArticle

Abstract

The majority of acute coronary syndromes are caused by plaque ruptures. Proteases secreted by macrophages play an important role in plaque ruptures by degrading extracellular matrix proteins in the fibrous cap. Matrix metalloproteinases have been shown to be markers for cardiovascular disease whereas the members of the cathepsin protease family are less studied.

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Subject classification (UKÄ) – MANDATORY

  • Cardiac and Cardiovascular Systems
Original languageEnglish
Pages (from-to)e000353
JournalOpen Heart
Volume3
Issue number1
Publication statusPublished - 2016
Publication categoryResearch
Peer-reviewedYes