High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families.
Research output: Contribution to journal › Article
Germline mutations in the tumour suppressor gene CDKN2A occur in 5-20% of familial melanoma cases. A single founder mutation, p.Arg112dup, accounts for the majority of CDKN2A mutations in Swedish carriers. In a national program, carriers of p.Arg112dup mutation have been identified. The aim of this study was to assess cancer risks in p.Arg112dup carriers and their first degree relatives (FDRs) and second degree relatives (SDRs).
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Journal of Medical Genetics|
|Publication status||Published - 2014|