Hollow implants in soft tissues allowing quantitative studies of cells and fluid at the implant interface

Research output: Contribution to journalArticle


In order to study the early cellular response in the fluid phase found close to implants in soft tissues, an experimental method using a hollow implant was developed. The fluid present in an interior chamber communicating with the exterior of the implant was analysed. Polymorphonuclear granulocytes (PMNGs) were predominant during the study (1-9 days). In titanium implants a slight increase in cell numbers with time was noted, whereas in polytetrafluoroethylene (PTFE) implants, a sharp increase in cell numbers was observed. Preliminary studies showed that sufficient amounts of fluid and cells could be retrieved for analysis of protein composition and inflammatory cell activation.


External organisations
  • External Organization - Unknown
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Bioengineering Equipment


  • titanium, Hollow implant, inflammatory cells, PTFE, fluid phase
Original languageEnglish
Pages (from-to)86-90
Issue number1
Publication statusPublished - 1988
Publication categoryResearch
Externally publishedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Bioimplant Research (013242910)