Hormone-Sensitive Lipase as Mediator of Lipolysis in Contracting Skeletal Muscle.

Research output: Contribution to journalReview article

Abstract

The authors propose that the enzyme hormone-sensitive lipase (HSL), which is the rate-limiting enzyme for hydrolysis of triacylglycerol in adipocytes, also regulates the intramyocellular triacylglycerol mobilization and is controlled by mechanisms similar to those regulating glycogen phosphorylase. From an exercise perspective, it is fascinating that the primary enzymatic setting allows simultaneous mobilization of all major extramuscular and intramuscular energy stores.

Details

Authors
  • Morten Donsmark
  • Jozef Langfort
  • Cecilia Holm
  • Thorkil Ploug
  • Henrik Galbo
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cell and Molecular Biology
Original languageEnglish
Pages (from-to)127-133
JournalExercise and Sport Sciences Reviews
Volume33
Issue number3
Publication statusPublished - 2005
Publication categoryResearch
Peer-reviewedYes