Host genetic resistance to symptomatic norovirus (GGII.4) infections in Denmark
Research output: Contribution to journal › Article
A total of 61 individuals involved in five norovirus outbreaks in Denmark were genotyped at nucleotides 428 and 571 of the FUT2 gene, determining secretor status, i.e., the presence of ABH antigens in secretions and on mucosa. A strong correlation (P = 0.003) was found between the secretor phenotype and symptomatic disease, extending previous knowledge and confirming that nonsense mutations in the FUT2 gene provide protection against symptomatic norovirus (GGII.4) infections.
|Research areas and keywords||
|Number of pages||3|
|Journal||Journal of Clinical Microbiology|
|Publication status||Published - 2007 Aug|