Human endogenous peptide p33 inhibits detrimental effects of LL-37 on osteoblast viability.

Research output: Contribution to journalArticle

Abstract

High levels of the antimicrobial peptide, LL-37, are detected in gingival crevicular fluid from patients with chronic periodontitis. LL-37 not only shows antimicrobial activity but also affects host-cell viability. The objective of the present study was to identify endogenous mechanisms that antagonize the detrimental effects of LL-37 on osteoblast viability, focusing on the human peptide p33 expressed on the surface of various cell types.

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Subject classification (UKÄ) – MANDATORY

  • Dentistry
Original languageEnglish
Pages (from-to)80-88
JournalJournal of Periodontal Research
Volume50
Issue number1
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Vascular Physiology (013212034), Mucosal biology (013212033), Division of Infection Medicine (BMC) (013024020)

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