Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies
Research output: Contribution to journal › Article
In this article, Roybon and colleagues developed a protocol to efficiently and rapidly generate hippocampus neurons from human induced pluripotent stem cells, which they used to model Alzheimer disease and develop a gene therapy approach to modulate the expression of genes involved in synaptic transmission.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Number of pages||18|
|Journal||Stem Cell Reports|
|Publication status||Published - 2020|