Immunsvar och inflammation vid Crohns sjukdom. Snart möjligt driva diagnostiken längre och utveckla mer specifika läkemedel

Research output: Contribution to journalArticle

Abstract

The chronic inflammation in Crohn's disease may be caused by aggressive response to bacterial antigens normal to the gut. Genetic and environmental factors modify the inflammatory response evoked by damage to the mucosal gut barrier. Genetic factors may also determine the subsequent course of chronic inflammation. Further elucidation of the pathogenesis might improve our understanding of the heterogenous nature of Crohn's disease, thus enabling the disease to be subtyped and individualised therapy directed primarily at down-regulation of helper T-cell-1 response to be developed.

Details

Authors
External organisations
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Gastroenterology and Hepatology

Keywords

  • English Abstract, Journal Article, Review
Translated title of the contributionImmune response and inflammation in Crohn disease. More detailed diagnostics and more specific drugs are soon to be available
Original languageSwedish
Pages (from-to)52-5
Number of pages4
JournalLakartidningen
Volume96
Issue number1-2
Publication statusPublished - 1999 Jan 6
Publication categoryResearch
Peer-reviewedNo
Externally publishedYes