Improved general and oral health in diabetic patients by an okinawan-based nordic diet: A pilot study

Research output: Contribution to journalArticle


Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND®). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce their insulin intake after two weeks with OBND®. The reduction was about 16 units which corresponds to a 34% relative reduction compared to the starting point (range 15–63%). Fasting blood glucose values fell (p = 0.035). Hemoglobin A1c (HbA1c) (p = 0.01), triglycerides (p = 0.05), and low-density lipoprotein (LDL) (p = 0.05) were also reduced. Bleeding on probing changed from ~28% before any dietary changes to ~13% after two weeks with OBND® (p = 0.01). The reduction in gingival bleeding was as substantial as might be expected from one session of professional tooth cleaning. Markers of inflammation were also reduced. The OBND® thus showed significant promise in alleviating the impact of diabetes on dental as well as general health.


  • Helene Holmer
  • Cecilia Widén
  • Viveca Wallin Bengtsson
  • Michael Coleman
  • Björn Wohlfart
  • Stig Steen
  • Rutger Persson
  • Klas Sjöberg
External organisations
  • Central Hospital Kristianstad
  • Kristianstad University
  • Aston University
  • Skåne University Hospital
  • University of Washington
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Endocrinology and Diabetes
  • Dentistry


  • Bleeding on probing, Clinical study, Cytokines, Diet, Metabolic disorder, Oral health
Original languageEnglish
Article number1949
JournalInternational Journal of Molecular Sciences
Issue number7
Publication statusPublished - 2018 Jul 3
Publication categoryResearch