In vitro-uptake of L-Dopa and catecholamines into the epidermal Langerhans cell

Research output: Contribution to journalArticle

Abstract

The Langerhans cells are capable of taking up L-dopa and the catecholamines dopamine and noradrenaline when exposed to these substances in vitro. Within the cell L-dopa is found in the cytoplasm as well as in the nucleus, whereas the catecholamines are confined to cytoplasmic granules. The L-dopa uptake is most probably carrier-mediated and the hypothesis is brought forward that L-dopa enters the cell by exchange diffusion. At present little is known about the nature of the amine uptake mechanism.

Details

Authors
Organisations
External organisations
  • Lund University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Dermatology and Venereal Diseases
  • Zoology
Original languageEnglish
Pages (from-to)31-35
JournalActa Dermatovenerologica Supplement
Volume79
Publication statusPublished - 1978
Publication categoryResearch
Peer-reviewedYes