Incidence of Intraocular Lens Exchange after Cataract Surgery

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Incidence of Intraocular Lens Exchange after Cataract Surgery. / Abdalla Elsayed, Maram E.A.; Ahmad, Khabir; Al-Abdullah, Abdulelah A.; Malik, Rizwan; Khandekar, Rajiv; Martinez-Osorio, Hernan; Mura, Marco; Schatz, Patrik.

In: Scientific Reports, Vol. 9, No. 1, 12877, 2019.

Research output: Contribution to journalArticle

Harvard

Abdalla Elsayed, MEA, Ahmad, K, Al-Abdullah, AA, Malik, R, Khandekar, R, Martinez-Osorio, H, Mura, M & Schatz, P 2019, 'Incidence of Intraocular Lens Exchange after Cataract Surgery', Scientific Reports, vol. 9, no. 1, 12877. https://doi.org/10.1038/s41598-019-49030-2

APA

Abdalla Elsayed, M. E. A., Ahmad, K., Al-Abdullah, A. A., Malik, R., Khandekar, R., Martinez-Osorio, H., ... Schatz, P. (2019). Incidence of Intraocular Lens Exchange after Cataract Surgery. Scientific Reports, 9(1), [12877]. https://doi.org/10.1038/s41598-019-49030-2

CBE

Abdalla Elsayed MEA, Ahmad K, Al-Abdullah AA, Malik R, Khandekar R, Martinez-Osorio H, Mura M, Schatz P. 2019. Incidence of Intraocular Lens Exchange after Cataract Surgery. Scientific Reports. 9(1). https://doi.org/10.1038/s41598-019-49030-2

MLA

Vancouver

Abdalla Elsayed MEA, Ahmad K, Al-Abdullah AA, Malik R, Khandekar R, Martinez-Osorio H et al. Incidence of Intraocular Lens Exchange after Cataract Surgery. Scientific Reports. 2019;9(1). 12877. https://doi.org/10.1038/s41598-019-49030-2

Author

Abdalla Elsayed, Maram E.A. ; Ahmad, Khabir ; Al-Abdullah, Abdulelah A. ; Malik, Rizwan ; Khandekar, Rajiv ; Martinez-Osorio, Hernan ; Mura, Marco ; Schatz, Patrik. / Incidence of Intraocular Lens Exchange after Cataract Surgery. In: Scientific Reports. 2019 ; Vol. 9, No. 1.

RIS

TY - JOUR

T1 - Incidence of Intraocular Lens Exchange after Cataract Surgery

AU - Abdalla Elsayed, Maram E.A.

AU - Ahmad, Khabir

AU - Al-Abdullah, Abdulelah A.

AU - Malik, Rizwan

AU - Khandekar, Rajiv

AU - Martinez-Osorio, Hernan

AU - Mura, Marco

AU - Schatz, Patrik

PY - 2019

Y1 - 2019

N2 - Intraocular lens (IOL) exchange after cataract surgery is unusual but may be associated with suboptimal visual outcome. The incidence of IOL exchange has not been consistently estimated. Such information is invaluable when counseling patients prior to cataract surgery. We examined the incidence of, and indications and risk factors for, IOL exchange after cataract surgery. We also assessed visual outcome of eyes that had an IOL exchange. A cohort design was used to estimate the incidence of IOL exchange and a case-control design to identify factors associated with it. All phacoemulsification surgeries with IOL (n = 17415 eyes) during 2010-2017 and those that had a subsequent IOL removal or replacement during the same time period were identified (n = 34 eyes). The incidence of IOL exchange was 2 per 1000 surgeries (95% confidence interval [CI] 1 to 3) over 8 years. Eyes that underwent subsequent IOL removal or replacement were compared with eyes that had cataract surgery only (n = 47) across demographic and clinical characteristics. In a binary logistic regression analysis, two factors were significantly associated with IOL exchange/removal: an adverse event during cataract surgery (adjusted odds ratio [aOR] 19.45; 95% CI 4.89-77.30, P < 0.001) and a pre-existing ocular comorbidity (aOR 10.70; 95% CI 1.69-67.63, P = 0.021). The effect of gender was marginally significant (P = 0.077). Eyes that underwent IOL exchange or explantation were nearly two and a half times more likely to have a final best-corrected visual acuity of <20/60 compared to those that had cataract surgery alone (adjusted RR 2.60 95% CI, 1.13-6.02; P = 0.025).

AB - Intraocular lens (IOL) exchange after cataract surgery is unusual but may be associated with suboptimal visual outcome. The incidence of IOL exchange has not been consistently estimated. Such information is invaluable when counseling patients prior to cataract surgery. We examined the incidence of, and indications and risk factors for, IOL exchange after cataract surgery. We also assessed visual outcome of eyes that had an IOL exchange. A cohort design was used to estimate the incidence of IOL exchange and a case-control design to identify factors associated with it. All phacoemulsification surgeries with IOL (n = 17415 eyes) during 2010-2017 and those that had a subsequent IOL removal or replacement during the same time period were identified (n = 34 eyes). The incidence of IOL exchange was 2 per 1000 surgeries (95% confidence interval [CI] 1 to 3) over 8 years. Eyes that underwent subsequent IOL removal or replacement were compared with eyes that had cataract surgery only (n = 47) across demographic and clinical characteristics. In a binary logistic regression analysis, two factors were significantly associated with IOL exchange/removal: an adverse event during cataract surgery (adjusted odds ratio [aOR] 19.45; 95% CI 4.89-77.30, P < 0.001) and a pre-existing ocular comorbidity (aOR 10.70; 95% CI 1.69-67.63, P = 0.021). The effect of gender was marginally significant (P = 0.077). Eyes that underwent IOL exchange or explantation were nearly two and a half times more likely to have a final best-corrected visual acuity of <20/60 compared to those that had cataract surgery alone (adjusted RR 2.60 95% CI, 1.13-6.02; P = 0.025).

U2 - 10.1038/s41598-019-49030-2

DO - 10.1038/s41598-019-49030-2

M3 - Article

VL - 9

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 12877

ER -