Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS)

Research output: Chapter in Book/Report/Conference proceedingBook chapter

Standard

Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS). / Johnsson, Åse; Angerås, Oskar; Blomberg, Anders; Erlinge, David; Flinck, Agneta; Janson, Christer; Markstad, Hanna; Persson, Jonas; Persson, H. Lennart; Swahn, Eva; Toren, Kjell; Vikgren, Jenny; Hansson, Mats G.; Bergström, Göran.

Incidental Radiological Findings. ed. / Sabine Weckbach . Springer, 2017. p. 91-101 (Medical Radiology).

Research output: Chapter in Book/Report/Conference proceedingBook chapter

Harvard

Johnsson, Å, Angerås, O, Blomberg, A, Erlinge, D, Flinck, A, Janson, C, Markstad, H, Persson, J, Persson, HL, Swahn, E, Toren, K, Vikgren, J, Hansson, MG & Bergström, G 2017, Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS). in S Weckbach (ed.), Incidental Radiological Findings. Medical Radiology, Springer, pp. 91-101. https://doi.org/10.1007/174_2016_52

APA

Johnsson, Å., Angerås, O., Blomberg, A., Erlinge, D., Flinck, A., Janson, C., ... Bergström, G. (2017). Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS). In S. Weckbach (Ed.), Incidental Radiological Findings (pp. 91-101). (Medical Radiology). Springer. https://doi.org/10.1007/174_2016_52

CBE

Johnsson Å, Angerås O, Blomberg A, Erlinge D, Flinck A, Janson C, Markstad H, Persson J, Persson HL, Swahn E, Toren K, Vikgren J, Hansson MG, Bergström G. 2017. Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS). Weckbach S, editor. In Incidental Radiological Findings. Springer. pp. 91-101. (Medical Radiology). https://doi.org/10.1007/174_2016_52

MLA

Johnsson, Åse et al. "Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS)". Weckbach , Sabine (ed.). Incidental Radiological Findings. Medical Radiology. Springer. 2017, 91-101. https://doi.org/10.1007/174_2016_52

Vancouver

Johnsson Å, Angerås O, Blomberg A, Erlinge D, Flinck A, Janson C et al. Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS). In Weckbach S, editor, Incidental Radiological Findings. Springer. 2017. p. 91-101. (Medical Radiology). https://doi.org/10.1007/174_2016_52

Author

Johnsson, Åse ; Angerås, Oskar ; Blomberg, Anders ; Erlinge, David ; Flinck, Agneta ; Janson, Christer ; Markstad, Hanna ; Persson, Jonas ; Persson, H. Lennart ; Swahn, Eva ; Toren, Kjell ; Vikgren, Jenny ; Hansson, Mats G. ; Bergström, Göran. / Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS). Incidental Radiological Findings. editor / Sabine Weckbach . Springer, 2017. pp. 91-101 (Medical Radiology).

RIS

TY - CHAP

T1 - Incidental findings and their handling in the Swedish CArdioPulmonary bioimage study (SCAPIS)

AU - Johnsson, Åse

AU - Angerås, Oskar

AU - Blomberg, Anders

AU - Erlinge, David

AU - Flinck, Agneta

AU - Janson, Christer

AU - Markstad, Hanna

AU - Persson, Jonas

AU - Persson, H. Lennart

AU - Swahn, Eva

AU - Toren, Kjell

AU - Vikgren, Jenny

AU - Hansson, Mats G.

AU - Bergström, Göran

PY - 2017

Y1 - 2017

N2 - The Swedish CArdioPulmonary bioImage Study (SCAPIS) combines the use of new imaging technologies, large-scale proteomics/metabolomics/genomics, and epidemiological analyses to extensively characterize a Swedish cohort of 30,000 men and women aged between 50 and 64 years. Its main aims are to improve risk prediction and to optimize our ability to study mechanisms of cardiopulmonary diseases. SCAPIS is currently recruiting at six sites in Sweden, and a pilot study was conducted in 2012 to test the feasibility of the comprehensive study protocol. In the planning phase, it was recognized that the detailed phenotyping used in SCAPIS would identify a large number of clinical findings in need of medical attention. This was confirmed by evaluation of results from the pilot study. Here we focus on pulmonary nodules and asymptomatic coronary artery stenosis. These clinical features were observed in a large number of participants, and the clinical handing and prognosis related to these observations are unclear. They thus posed great challenges for the study in their practical and ethical handling. This chapter describes how we developed procedures to handle these findings based on existing evidence and expert consensus as well as deliberations on ethical issues.

AB - The Swedish CArdioPulmonary bioImage Study (SCAPIS) combines the use of new imaging technologies, large-scale proteomics/metabolomics/genomics, and epidemiological analyses to extensively characterize a Swedish cohort of 30,000 men and women aged between 50 and 64 years. Its main aims are to improve risk prediction and to optimize our ability to study mechanisms of cardiopulmonary diseases. SCAPIS is currently recruiting at six sites in Sweden, and a pilot study was conducted in 2012 to test the feasibility of the comprehensive study protocol. In the planning phase, it was recognized that the detailed phenotyping used in SCAPIS would identify a large number of clinical findings in need of medical attention. This was confirmed by evaluation of results from the pilot study. Here we focus on pulmonary nodules and asymptomatic coronary artery stenosis. These clinical features were observed in a large number of participants, and the clinical handing and prognosis related to these observations are unclear. They thus posed great challenges for the study in their practical and ethical handling. This chapter describes how we developed procedures to handle these findings based on existing evidence and expert consensus as well as deliberations on ethical issues.

KW - Cardiovascular

KW - Epidemiology

KW - Metabolism

KW - Pulmonary

KW - Study design

UR - http://www.scopus.com/inward/record.url?scp=85019102819&partnerID=8YFLogxK

U2 - 10.1007/174_2016_52

DO - 10.1007/174_2016_52

M3 - Book chapter

SN - 978-3-319-42579-5

T3 - Medical Radiology

SP - 91

EP - 101

BT - Incidental Radiological Findings

A2 - Weckbach , Sabine

PB - Springer

ER -