Increased expression of upstream TH2-cytokines in a mouse model of viral-induced asthma exacerbation.
Research output: Contribution to journal › Article
Exacerbations of asthma caused by respiratory viral infections are serious conditions in need of novel treatment. To this end animal models of asthma exacerbations are warranted. We have shown that dsRNA challenges or rhinoviral infection produce exacerbation effects in mice with ovalbumin (OVA)-induced allergic asthma. However, house dust mite (HDM) is a more human asthma-relevant allergen than OVA. We thus hypothesised that dsRNA challenges in mice with HDM-induced experimental asthma would produce important translational features of asthma exacerbations.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Journal of Translational Medicine|
|Publication status||Published - 2016|
Related research output
Irma Mahmutovic Persson, 2016, Lund: Lund University, Faculty of Medicine. 122 p.
Research output: Thesis › Doctoral Thesis (compilation)