Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia

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Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia. / Andersson, Maria; Bergendorff, Ola; Nielsen, Mogens; Sterner, Olov; Witt, Robin; Ai, Jinglu; Lu, Aiping; Wang, An Min.

In: Phytochemistry, Vol. 38, No. 4, 1995, p. 835-836.

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Andersson, Maria ; Bergendorff, Ola ; Nielsen, Mogens ; Sterner, Olov ; Witt, Robin ; Ai, Jinglu ; Lu, Aiping ; Wang, An Min. / Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia. In: Phytochemistry. 1995 ; Vol. 38, No. 4. pp. 835-836.

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TY - JOUR

T1 - Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia

AU - Andersson, Maria

AU - Bergendorff, Ola

AU - Nielsen, Mogens

AU - Sterner, Olov

AU - Witt, Robin

AU - Ai, Jinglu

AU - Lu, Aiping

AU - Wang, An Min

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)

PY - 1995

Y1 - 1995

N2 - S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.

AB - S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.

U2 - 10.1016/0031-9422(94)00771-K

DO - 10.1016/0031-9422(94)00771-K

M3 - Article

VL - 38

SP - 835

EP - 836

JO - Phytochemistry

T2 - Phytochemistry

JF - Phytochemistry

SN - 0031-9422

IS - 4

ER -