Injectable cryogels in biomedicine

Research output: Contribution to journalReview article


Cryogels are interconnected macroporous materials that are synthesized from a monomer solution at sub-zero temperatures. Cryogels, which are used in various applications in many research areas, are frequently used in biomedicine applications due to their excellent properties, such as biocompatibility, physical resistance and sensitivity. Cryogels can also be prepared in powder, column, bead, sphere, membrane, monolithic, and injectable forms. In this review, various examples of recent developments in biomedical applications of injectable cryogels, which are currently scarce in the literature, made from synthetic and natural polymers are discussed. In the present review, several biomedical applications of injectable cryogels, such as tissue engineering, drug delivery, therapeutic, therapy, cell transplantation, and immunotherapy, are emphasized. Moreover, it aims to provide a different perspective on the studies to be conducted on injectable cryogels, which are newly emerging trend.


  • Duygu Çimen
  • Merve Asena Özbek
  • Nilay Bereli
  • Bo Mattiasson
  • Adil Denizli
External organisations
  • Hacettepe University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Medical Materials


  • Biomedicine application, Injectable cryogel, Polymer, Supermacroporous
Original languageEnglish
Article number38
Issue number2
Publication statusPublished - 2021 Jun
Publication categoryResearch