Integrated acoustic sample preparation for rapid sepsis diagnostics

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

Abstract

We present a novel, integrated microfluidic system based on acoustophoretic cell-handling that detects bacteria in whole blood in less than 2 hours, substantially faster than current standard methods for detection of sepsis-causing bacteria. Bacteria are acoustically separated from 1 ml blood, enriched by acoustic trapping and finally detected using a dry-reagent PCR-chip.

Details

Authors
Organisations
External organisations
  • University of Turku
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Biomedical Laboratory Science/Technology

Keywords

  • Acoustic separation, Acoustic trapping, Bacteria, Blood, Integrated, PCR, Sepsis
Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages294-296
Number of pages3
ISBN (Electronic)9780979806476
ISBN (Print)9781634396974
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 2014 Oct 262014 Oct 30
Conference number: 18

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period2014/10/262014/10/30