Intensified Tuberculosis Case-Finding in HIV-Positive Adults Managed at Ethiopian Health Centers: Diagnostic Yield of Xpert MTB/RIF Compared with Smear Microscopy and Liquid Culture.

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Abstract

Detection of active tuberculosis (TB) before antiretroviral therapy (ART) initiation is important, but optimal diagnostic methods for use in resource-limited settings are lacking. We assessed the prevalence of TB, evaluated the diagnostic yield of Xpert MTB/RIF in comparison with smear microscopy and culture, and the impact of Xpert results on clinical management in HIV-positive adults eligible for ART at health centers in a region of Ethiopia.

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Subject classification (UKÄ) – MANDATORY

  • Microbiology in the medical area
  • Infectious Medicine
Original languageEnglish
Article numbere85478
JournalPLoS ONE
Volume9
Issue number1
Publication statusPublished - 2014
Publication categoryResearch
Peer-reviewedYes

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