International comparison of trends in patients commencing renal replacement therapy by primary renal disease

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title = "International comparison of trends in patients commencing renal replacement therapy by primary renal disease",
abstract = "Aim: To examine international time trends in the incidence of renal replacement therapy (RRT) for end-stage renal disease (ESRD) by primary renal disease (PRD). Methods: Renal registries reporting on patients starting RRT per million population for ESRD by PRD from 2005 to 2014, were identified by internet search and literature review. The average annual percentage change (AAPC) with a 95{\%} confidence interval (CI) of the time trends was computed using Joinpoint regression. Results: There was a significant decrease in the incidence of RRT for ESRD due to diabetes mellitus (DM) in Europe (AAPC = −0.9; 95{\%}CI −1.3; −0.5) and to hypertension/renal vascular disease (HT/RVD) in Australia (AAPC = −1.8; 95{\%}CI −3.3; −0.3), Canada (AAPC = −2.9; 95{\%}CI −4.4; −1.5) and Europe (AAPC = −1.1; 95{\%}CI −2.1; −0.0). A decrease or stabilization was observed for glomerulonephritis in all regions and for autosomal dominant polycystic kidney disease (ADPKD) in all regions except for Malaysia and the Republic of Korea. An increase of 5.2–16.3{\%} was observed for DM, HT/RVD and ADPKD in Malaysia and the Republic of Korea. Conclusion: Large international differences exist in the trends in incidence of RRT by primary renal disease. Mapping of these international trends is the first step in defining the causes and successful preventative measures of CKD.",
keywords = "diabetes mellitus, hypertension, primary renal disease, renal replacement therapy, trends, worldwide",
author = "Stel, {Vianda S.} and Ryan Awadhpersad and Maria Pippias and Manuel Ferrer-Alamar and Patrik Finne and Fraser, {Simon D.} and Heaf, {James G.} and Hemmelder, {Marc H.} and Alberto Mart{\'i}nez-Castelao and {de Meester}, Johan and Runolfur Palsson and Prischl, {Friedrich C.} and M{\aa}rten Segelmark and Traynor, {Jamie P.} and Rafael Santamaria and Reis{\ae}ter, {Anna Varberg} and Massy, {Ziad A.} and Jager, {Kitty J.}",
year = "2019",
doi = "10.1111/nep.13531",
language = "English",
volume = "24",
pages = "1064--1076",
journal = "Nephrology",
issn = "1320-5358",
publisher = "Wiley-Blackwell",
number = "10",