Introducing PIONEER: a project to harness big data in prostate cancer research

Research output: Contribution to journalArticle


Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Programme (BD4BO), the overarching goal of PIONEER is to provide high-quality evidence on prostate cancer management by unlocking the potential of big data. The project has identified critical evidence gaps in prostate cancer care, via a detailed prioritization exercise including all key stakeholders. By standardizing and integrating existing high-quality and multidisciplinary data sources from patients with prostate cancer across different stages of the disease, the resulting big data will be assembled into a single innovative data platform for research. Based on a unique set of methodologies, PIONEER aims to advance the field of prostate cancer care with a particular focus on improving prostate-cancer-related outcomes, health system efficiency by streamlining patient management, and the quality of health and social care delivered to all men with prostate cancer and their families worldwide.


  • Muhammad Imran Omar
  • Monique J. Roobol
  • Maria J. Ribal
  • Thomas Abbott
  • Paul Michael Agapow
  • Sonia Araujo
  • Alex Asiimwe
  • Charles Auffray
  • Irina Balaur
  • Katharina Beyer
  • Chiara Bernini
  • Anders Bjartell
  • Alberto Briganti
  • John Edward Butler-Ransohoff
  • Riccardo Campi
  • Marinel Cavelaars
  • Bertrand De Meulder
  • Zsuzsanna Devecseri
  • Marc Dietrich Voss
  • Konstantinos Dimitropoulos
  • Susan Evans-Axelsson
  • Billy Franks
  • Louise Fullwood
  • Denis Horgan
  • Emma Jane Smith
  • Amit Kiran
  • Kati Kivinummi
  • Mark Lambrecht
  • Doron Lancet
  • Peter Lindgren
  • Sara MacLennan
  • Steven MacLennan
  • Maria Manuela Nogueira
  • Fredrik Moen
  • Maxim Moinat
  • Kishore Papineni
  • Christian Reich
  • Kristin Reiche
  • Stijn Rogiers
  • Claudio Sartini
  • Kees van Bochove
  • Femke van Diggelen
  • Mieke Van Hemelrijck
  • Hein Van Poppel
  • Jihong Zong
  • James N’Dow
  • The PIONEER Consortium
External organisations
  • University of Aberdeen
  • Erasmus University Medical Center
  • Imperial College London
  • IQVIA Inc.
  • Bayer Pharma AG
  • King's College London
  • Vita-Salute San Raffaele University
  • The Hyve
  • Sanofi S.A., France
  • European Association of Urology, Research Foundation
  • University of Tampere
  • SAS Institute nv/sa
  • Weizmann Institute of Science Israel
  • IHE – The Swedish Institute for Health Economics
  • ttopstart
  • Astellas Pharma Europe
  • Association EISBM
  • European Alliance for Personalised Medicine
  • Pinsent Masons LLP
  • Fraunhofer Institute for Cell Therapy and Immunology
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology
  • Urology and Nephrology
Original languageEnglish
Pages (from-to)351-361
Number of pages11
JournalNature Reviews Urology
Issue number6
Publication statusPublished - 2020
Publication categoryResearch