Involvement of mitochondria in the control of plant cell NAD(P)H reduction levels.

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Abstract

NADPH and NADH mediate reductant flow between cellular processes, linking central carbon and energy metabolism with intermediary metabolism, stress defence and development. Recent investigations have revealed paths of functional interactions, and have suggested that mitochondrial NADPH oxidation, especially together with the oxidative pentose phosphate pathway, is an important regulator of the cytosolic NADPH reduction level. Furthermore, stress-dependent metabolic pathways substantially affect the NADPH reduction level in particular physiological situations. The mitochondrial impact on the NADPH reduction level provides a model example of the physiological significance of the mitochondrial NAD(P)H dehydrogenase set-up, which is more complex in plants than in other organisms.

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Subject classification (UKÄ) – MANDATORY

  • Biochemistry and Molecular Biology

Keywords

  • carbon metabolism, mitochondrial electron transport, NAD(P)H, redox homoeostasis, stress.
Original languageEnglish
Pages (from-to)661-666
JournalBiochemical Society Transactions
Volume38
Issue number2
Publication statusPublished - 2010
Publication categoryResearch
Peer-reviewedYes