LD-isoenzym i uterusaspirat potentiell markör för endometriecancer. Utredning av postmenopausal blödning kan bli enklare och billigare

Research output: Contribution to journalArticle

Abstract

n diagnosing endometrial carcinoma in women with postmenopausal bleeding analysis of lactate dehydrogenase, LD, isoenzymes in uterine aspirates appeared to have 100 per cent sensitivity and negative predictive value combined with high specificity and positive predictive value. Determination of the LD-profile is suggested as a marker for endometrial carcinoma in women with postmenopausal bleeding. Transvaginal ultrasonography might be combined with determination of the LD-isoenzyme profile to secure the diagnosis of endometrial malignancy in order to minimize the use of other more invasive diagnostic methods.

Details

Authors
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Obstetrics, Gynecology and Reproductive Medicine

Keywords

  • Tumor Markers, Middle Aged, L-Lactate Dehydrogenase: analysis, Isoenzymes: analysis, Humans, Female, English Abstract, Endometrial Neoplasms: enzymology, Aged, Sensitivity and Specificity, Postmenopause, Predictive Value of Tests, Biological: analysis, Uterine Hemorrhage: diagnosis, Uterine Hemorrhage: enzymology
Translated title of the contributionLD isoenzyme in uterine aspirates a potential marker of endometrial cancer. Investigation of postmenopausal bleeding can be simpler and cheaper
Original languageSwedish
Pages (from-to)2141-4
JournalLäkartidningen
Volume102
Issue number30-31
Publication statusPublished - 2005
Publication categoryResearch
Peer-reviewedYes