Lean ApoM−/− Mice with Hyperactive Brown Adipose Tissue

Research output: Contribution to journalArticle

Abstract

In Cell Reports, Christoffersen et al. [1] demonstrate that sphingosine 1-phosphate (S1P) bound to apolipoprotein M (apoM) regulates the activity and mass of brown adipose tissue (BAT). They found mice lacking apoM to have hyperactive BAT with high triglyceride (TG) utilization, resulting in low white adipose tissue (WAT) mass and low body weight.

Details

Authors
Organisations
External organisations
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cell and Molecular Biology

Keywords

  • knockout mice, brown adipose tissue
Original languageEnglish
Pages (from-to)283-284
JournalTrends in Endocrinology and Metabolism
Volume29
Issue number5
Early online date2018 Mar 13
Publication statusPublished - 2018 May
Publication categoryResearch
Peer-reviewedYes