Leukemia

Research output: Chapter in Book/Report/Conference proceedingBook chapter

Abstract

Leukemias are a group of life threatening malignant disorders of the blood and bone marrow. In the adolescent and young adult (AYA) population, the acute leukemias are most prevalent, with chronic myeloid leukemia being infrequently seen. Factors associated with more aggressive disease biology tend to increase in frequency with increasing age, whilst tolerability of treatment strategies decreases. There are also challenges regarding the effective delivery of therapy specific to the AYA group, consequences on the unique psychosocial needs of this age group, including compliance. This chapter reviews the current status of epidemiology, pathophysiology, treatment strategies and outcomes of AYA leukemia, with a focus on acute lymphoblastic leukemia and acute myeloid leukemia.

Details

Authors
Organisations
External organisations
  • Royal Free Hospital
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology
  • Hematology
Original languageEnglish
Title of host publicationTumors in Adolescents and Young Adults
EditorsDP Stark, G Vassal
Place of PublicationBasel
PublisherS. Karger AG
Pages87-100
Number of pages14
Volume43
ISBN (Electronic)978-3-318-05912-0
ISBN (Print)978-3-318-05911-3
Publication statusPublished - 2016
Publication categoryResearch
Peer-reviewedYes