Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke.

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Abstract

Atherosclerotic plaques with a low content of connective tissue proteins are believed to have an increased risk of rupture and to give rise to clinical events. The aim of the present study was to investigate if the content of elastin, collagen and of the matrix metalloproteinase (MMP) -1, -3, -9 and -12 in plaques removed at surgery can be associated with the occurrence of ipsilateral symptoms.

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  • Cardiac and Cardiovascular Systems
Original languageEnglish
Article numbere0121086
JournalPLoS ONE
Volume10
Issue number3
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes

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