Lower breast cancer survival in mothers of children with a malignancy: a national study.

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Bibtex

@article{28ef7775876d42ad973a5ef7305c028f,
title = "Lower breast cancer survival in mothers of children with a malignancy: a national study.",
abstract = "As it is unclear if hereditary factors affect breast cancer survival, this was compared using fertility and cancer registry data, among all women so diagnosed during 1961-1999 in Sweden, having a child with childhood cancer (<or=20 years of age; n=254) and with that of other women (n=74,781). Those having a child with a childhood malignancy had a significantly worse survival than other women, relative risk (RR)=1.25, 95% CI 1.02-1.55, P<0.04, adjusted for age at diagnosis, year of diagnosis, parity and time since last pregnancy. Childhood sarcomas or acute myeloid leukaemia seemed to be most associated with a worse survival in the mother (RR=1.38 and 1.69, respectively). The lower survival of the mother was present for breast cancer diagnosed both before and after 50 years of age. The Li-Fraumeni syndrome and possibly other genetic disorders may lower breast cancer survival.",
author = "H{\aa}kan Olsson and Susanne Magnusson and Anna Bladstr{\"o}m",
year = "2008",
doi = "10.1038/sj.bjc.6604350",
language = "English",
volume = "98",
pages = "1876--1878",
journal = "British Journal of Cancer",
issn = "1532-1827",
publisher = "Nature Publishing Group",
number = "11",

}