Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries.

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Abstract

Male-female differences may significantly impact stroke prevention and treatment in men and women, however underlying mechanisms for sexual dimorphism in stroke are not understood. We previously found in males that cerebral ischemia upregulates contractile receptors in cerebral arteries, which is associated with lower blood flow. The present study investigates if cerebral arteries from men and women differ in cerebrovascular receptor upregulation.

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  • Other Clinical Medicine
  • Neurology
  • Surgery
Original languageEnglish
Article numbere62698
JournalPLoS ONE
Volume8
Issue number4
Publication statusPublished - 2013
Publication categoryResearch
Peer-reviewedYes

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