Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly

Research output: Contribution to journalArticle


Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non-organic mental diseases. This paper reviews the literature relevant for markers of cobalamin/folate status and their relation to neuropsychiatric symptoms in the elderly. Plasma homocysteine, a marker of cobalamin/folate status, is frequently increased in psychogeriatric patients. Among markers of cobalamin/folate status, plasma homocysteine shows the best association with neuropsychiatric dysfunction.


Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Geriatrics
  • Psychiatry


  • blood, cobalamin, folate, homocysteine, methylmalonic acid, plasma, psychogeriatric patients
Original languageEnglish
Pages (from-to)873-878
JournalInternational Journal of Geriatric Psychiatry
Issue number9
Publication statusPublished - 2001
Publication categoryResearch

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Department of Psychogeriatrics (013304000)