Maternal use of oral decongestants and delivery outcome

Research output: Contribution to journalArticle


The study extends a previous investigation on the use of oral decongestants during pregnancy with another 1 000 women (1 017 infants) who reported the use of such drugs in early pregnancy and 1 125 women (1 145 infants) who had such drugs prescribed later in pregnancy. The results on the beneficial delivery outcome after late use of the drugs with a reduced rate of preterm birth and low birth weight were verified and it was also shown that the rates of large-for-gestational age and heavy infants were increased. After early use of such drugs, no increased risk of congenital malformation was seen and previously published data on an association with certain malformations, thought to be due to vascular disruption, could not be supported. It is suggested that pregnancy rhinitis as an indication for the use of oral decongestants could be associated with a well functioning placenta and a good delivery outcome.


  • Bengt Källén
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Obstetrics, Gynecology and Reproductive Medicine


  • malformations, congenital, low birth weight, oral decongestants, preterm birth
Original languageSpanish
Pages (from-to)41-45
JournalSalud i Ciencia
Issue number1
Publication statusPublished - 2009
Publication categoryResearch