Measurement of pulmonary density by means of X-ray computerized tomography. Relation to pulmonary mechanics in normal subjects

Research output: Contribution to journalArticle

Abstract

We examined the relationship between pulmonary density, measured with computerized tomography, and pulmonary mechanics (static pulmonary volume; pulmonary resistance) in 39 normal subjects (20 nonsmokers and 19 smokers). Pulmonary density decreased with increasing static elastic recoil pressure, and smokers consistently showed higher pulmonary density than nonsmokers. Pulmonary density, measured at full inspiration, correlated inversely with total lung capacity. Pulmonary density showed a ventrodorsal gradient, which was greater at low elastic recoil pressure than at high recoil pressure. The study shows that pulmonary density is related to the mechanical properties of the lung in normal subjects. Increased pulmonary density appears to be a sensitive indicator of pulmonary damage induced by smoking. Further studies of the relationship between pulmonary density and pulmonary mechanics in disease seem warranted.

Details

Authors
Organisations
External organisations
  • Lund University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Respiratory Medicine and Allergy

Keywords

  • Aged, Biomechanical Phenomena, Humans, Lung, Lung Compliance, Lung Volume Measurements, Male, Middle Aged, Smoking, Tomography, X-Ray Computed, Journal Article
Original languageEnglish
Pages (from-to)387-91
Number of pages5
JournalChest
Volume90
Issue number3
Publication statusPublished - 1986 Sep
Publication categoryResearch
Peer-reviewedYes