Measurements of urea and glucose in aqueous solutions with dual-beam near-infrared Fourier transform spectroscopy

Research output: Contribution to journalArticle

Abstract

This study investigates the use of a dual-beam, optical null, FT-IR spectrometer to measure trace organic components in aqueous solutions in the combination band region 5000-4000 cm(-1). The spectrometer may be used for both single- and dual-beam measurements, thereby facilitating comparison of these two modes of operation. The concentrations of aqueous solutions of urea and glucose in the ranges 0-40 mg/dL and 0-250 mg/dL, respectively, were determined by principal component regression using both modes. The dual-beam technique eliminated instrumental variations present in the single-beam measurements that must be taken into account when quantifying trace components from single-beam spectra. The data obtained with the dual-beam technique resulted in more stable calibration models based on principal component regression. These calibration models need fewer factors and yield lower prediction errors than those based on traditional single-beam data.

Details

Authors
  • Peter Snoer Jensen
  • Jimmy Bak
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Atom and Molecular Physics and Optics

Keywords

  • optical null, dual-beam, near-infrared, FT-IR, glucose, urea, aqueous solutions, optical subtraction
Original languageEnglish
Pages (from-to)1593-1599
JournalApplied Spectroscopy
Volume56
Issue number12
Publication statusPublished - 2002
Publication categoryResearch
Peer-reviewedYes

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