Medical Applications of Laser Spectroscopy
Research output: Contribution to journal › Article
Lasers are finding many applications in medicine and biology. While most laser use focuses on the heat generation of the laser beam interacting with tissue, spectroscopic aspects play a more dominating part in a number of emerging applications. Tumour-seeking agents, such as hematoporphyrin derivative (HPD), in combination with laser radiation provide new possibilities for cancer tumour detection and treatment. The fluorescence emission from tissue irradiated with UV light can be used for tumour localization. Natural tissue fluorescence as well as fluorescence due to injected HPD can be utilized. Results from studies on animals and from clinical applications are reported. The use of fluorescence for identifying atherosclerotic plaque in human vessels is illustrated. Spectroscopic analysis of the laser-induced plasma obtained when a high-power, pulsed laser beam interacts with tissue is also discussed with applications to plaque removal and laser fragmentation of kidney- and gall-stones.