Metabolic fate of C-14-labelled chlorinated and non-chlorinated fatty acids in goldfish (Carassius auratus)

Research output: Contribution to journalArticle

Abstract

In order to study the metabolic fate of chlorinated fatty acids in fish, goldfish were fed either 9,10-dichlorostearic acid or oleic acid, chosen as the unchlorinated analogue, both radiolabelled at either the carboxyl (1st) or the terminal (18th) carbon of the fatty acid chain. By keeping the fish in hermetically closed aquaria, all the respired, assimilated and excreted radioactivity could be accounted for. Fish fed 9,10-dichlorostearic acid labelled in the terminal end respired radioactive CO2 to a much lower degree than fish fed the other test compounds. As a consequence, the radioactivity bound in lipids was higher in the group of fish fed dichlorostearic acid labelled in the terminal end. It is suggested that the chlorine atoms in the middle of the carbon chain obstruct the metabolic turn-over of 9,10-dichlorostearic acid, which may have an impact on the residence time of these compounds in the ecosystem.

Details

Authors
  • Helena Björn van Praagh
  • Göran Ewald
  • P Sundin
  • Clas Wesén
  • J Skramstad
  • P Froyen
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Social Sciences Interdisciplinary
  • Ecology
  • Analytical Chemistry
  • Chemical Engineering
Original languageEnglish
Pages (from-to)13-20
JournalFish Physiology & Biochemistry
Volume30
Issue number1
Publication statusPublished - 2004
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Analytical Chemistry (S/LTH) (011001004), Chemical Ecology/Ecotoxicology (Closed 2011) (011006020), Chemical Engineering (011001014), LUCSUS (Lund University Centre for Sustainability Studies) (016508030), Department of Biology (000016100)