Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression.

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Abstract

Oral squamous cell carcinoma (OSCC) constitutes 90% of all cancers in the oral cavity, and the prognosis for patients diagnosed with OSCC is still poor. The identification of novel therapeutic targets and prognostic markers for OSCC is therefore essential. Previous studies of OSCC revealed an increased expression of WNT5A in the tumor tissue. However, no functional studies of WNT5A-induced effects in OSCC have been performed.

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  • Cancer and Oncology
Original languageEnglish
Pages (from-to)776-784
JournalJournal of Oral Pathology & Medicine
Volume44
Issue number10
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes