MIRD Pamphlet No. 24: Guidelines for Quantitative I-131 SPECT in Dosimetry Applications

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Abstract

The reliability of radiation dose estimates in internal radionuclide therapy is directly related to the accuracy of activity estimates obtained at each imaging time point. The recently published MIRD pamphlet no. 23 provided a general overview of quantitative SPECT imaging for dosimetry. The present document is the first in a series of isotope-specific guidelines that will follow MIRD 23 and focuses on one of the most commonly used therapeutic radionuclides, I-131. The purpose of this document is to provide guidance on the development of protocols for quantitative I-131 SPECT in radionuclide therapy applications that require regional (normal organs, lesions) and 3-dimensional dosimetry.

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Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Radiology, Nuclear Medicine and Medical Imaging

Keywords

  • MIRD, I-131, quantitative SPECT, SPECT/CT, dosimetry
Original languageEnglish
Pages (from-to)2182-2188
JournalJournal of Nuclear Medicine
Volume54
Issue number12
Publication statusPublished - 2013
Publication categoryResearch
Peer-reviewedYes