Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function
Research output: Contribution to journal › Article
HSC aging is clinically associated with risk of anemia, immune compromise, and malignancy. Mansell et al. show that mitochondrial activity is directly linked to age-related performance of HSCs and that its perturbation has direct consequences for HSC function, resulting in alleviation or prevention of hematopoietic aging.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Cell Stem Cell|
|Early online date||2020 Oct 20|
|Publication status||Published - 2021|