Mollisianitrile, a new antibiotic from Mollisia sp A59-96

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Abstract

Mollisianitrile (1), a new antibiotic was isolated from the fermentation broth of Mollisa sp. A59-96 together with the two known isocoumarins 2 and 3. 1 exhibited antimicrobial, cytotoxic, and phytotoxic activities. 1 contains a reactive propiolonitrile moiety which is believed to be responsible for its antibiotic activities. Upon incubation with L-cysteine the biological activity was lost.

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Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry

Keywords

  • antimicrobial and cytotoxic activities, mollisia, mollisianitrile
Original languageEnglish
Pages (from-to)567-570
JournalZeitschrift fuer Naturforschung. Section C: A Journal of Biosciences
Volume62
Issue number7-8
Publication statusPublished - 2007
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)