Monitoring Low Molecular Weight Heparins at Therapeutic Levels: Dose-Responses of, and Correlations and Differences between aPTT, Anti-Factor Xa and Thrombin Generation Assays.

Research output: Contribution to journalArticle

Abstract

Low molecular weight heparins (LMWH's) are used to prevent and treat thrombosis. Tests for monitoring LMWH's include anti-factor Xa (anti-FXa), activated partial thromboplastin time (aPTT) and thrombin generation. Anti-FXa is the current gold standard despite LMWH's varying affinities for FXa and thrombin.

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Subject classification (UKÄ) – MANDATORY

  • Anesthesiology and Intensive Care
  • Hematology
  • Medicinal Chemistry
Original languageEnglish
Article numbere0116835
JournalPLoS ONE
Volume10
Issue number1
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes

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