Monte Carlo simulations of Donnan equilibrium in cartilage
Research output: Contribution to journal › Article
(23) Na magnetic resonance imaging and the delayed gadolinium-enhanced magnetic resonance imaging methods to investigate cartilage can be used to determine the fixed charge density of cartilage. The methods give results that differ by a factor of 2. In this study, we use Monte Carlo simulations on a model system of cartilage and find that the difference originates from the Coulombic intermolecular interactions between the ions in the cartilage, and in the synovial fluid. Those interactions are neglected in the standard Donnan analysis that generally is adopted to evaluate magnetic resonance imaging data. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Magnetic Resonance in Medicine|
|Publication status||Published - 2012|
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Theoretical Chemistry (S) (011001039), Physical Chemistry 1 (S) (011001006)
Related research output
Ions in models of articular cartilage: The importance of electrostatic interactions for transport and equilibrium distributionAlgotsson, J., 2017 Jan, Lund: Lund University, Faculty of Science, Department of Chemistry, Division of Physical Chemistry.
Research output: Thesis › Doctoral Thesis (compilation)