Axonal growth and guidance were studied on different micro- and nanostructured surfaces. Nanoimprinted grooves in a polymer, epitaxial III/V nanowires, porous silicon patterns, and chemically altered surfaces were all shown to induce axonal guidance. Neurons were also found to be able to attach and grow on gallium phosphide nanowires without compromising cell survival. The results are important for the construction of a new generation of neuroelectrical interfaces, including high spatial resolution electrodes. The advantages of the different nanostructured surfaces are discussed.
|Title of host publication||Journal of Vacuum Science and Technology B|
|Publisher||American Institute of Physics|
|Publication status||Published - 2008|
|Event||52nd International Conference on Electron, Ion and Photon Beam Technology and Nanofabrication - Portland, OR|
Duration: 2008 May 27 → 2008 May 30
|Conference||52nd International Conference on Electron, Ion and Photon Beam Technology and Nanofabrication|
|Period||2008/05/27 → 2008/05/30|