Nanotubes and bilayers in a model peptide system

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Nanotubes and bilayers in a model peptide system. / Cenker, Celen; Bucak, Seyda; Olsson, Ulf.

In: Soft Matter, Vol. 7, No. 10, 2011, p. 4868-4875.

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Cenker, Celen ; Bucak, Seyda ; Olsson, Ulf. / Nanotubes and bilayers in a model peptide system. In: Soft Matter. 2011 ; Vol. 7, No. 10. pp. 4868-4875.

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TY - JOUR

T1 - Nanotubes and bilayers in a model peptide system

AU - Cenker, Celen

AU - Bucak, Seyda

AU - Olsson, Ulf

PY - 2011

Y1 - 2011

N2 - The trifluoroacetate (tfa) salt of the peptide (ala)(6)lys self-assembles in water into very long, hollow nanotubes with a radius R = 26 nm, above a critical aggregation concentration (volume fraction), phi(cac) = 0.10. The peptides carry a net positive charge that ensures colloidal stability of the self-assembly structures through a long-range electrostatic repulsion. There is only a weak temperature dependence of phi(cac) from which an enthalpy of aggregation of -k(B)T per molecule is estimated. SAXS data show that the thickness of the nanotube wall, delta, is less than 1 nm indicating that the peptides form a monolayer in the nanotube wall. The nanotubes have a very large aspect ratio and form an ordered nematic or hexagonal phase. Because of the low delta/R ratio, the nanotube volume fraction grows very rapidly with increasing peptide concentration, phi, and reaches close packing already at phi = 0.15. When increasing the concentration further, there is a phase transition to a novel lamellar phase where the peptide molecules form bilayers consisting of two, presumably oppositely oriented, monolayers.

AB - The trifluoroacetate (tfa) salt of the peptide (ala)(6)lys self-assembles in water into very long, hollow nanotubes with a radius R = 26 nm, above a critical aggregation concentration (volume fraction), phi(cac) = 0.10. The peptides carry a net positive charge that ensures colloidal stability of the self-assembly structures through a long-range electrostatic repulsion. There is only a weak temperature dependence of phi(cac) from which an enthalpy of aggregation of -k(B)T per molecule is estimated. SAXS data show that the thickness of the nanotube wall, delta, is less than 1 nm indicating that the peptides form a monolayer in the nanotube wall. The nanotubes have a very large aspect ratio and form an ordered nematic or hexagonal phase. Because of the low delta/R ratio, the nanotube volume fraction grows very rapidly with increasing peptide concentration, phi, and reaches close packing already at phi = 0.15. When increasing the concentration further, there is a phase transition to a novel lamellar phase where the peptide molecules form bilayers consisting of two, presumably oppositely oriented, monolayers.

U2 - 10.1039/c0sm01186j

DO - 10.1039/c0sm01186j

M3 - Article

VL - 7

SP - 4868

EP - 4875

JO - Soft Matter

JF - Soft Matter

SN - 1744-6848

IS - 10

ER -