Neuropsychological tests as discriminators between dementia of Alzheimer type and frontotemporal dementia

Research output: Contribution to journalArticle

Abstract

The aim of this study was to examine whether cognitive test performance alone could distinguish patients with dementia of Alzheimer type (DAT) from those with frontotemporal dementia (FTD). Scores from three neuropsychological tests were used as discriminating variables in 28 cases with postmortem verified diagnoses. The selected tests measured verbal ability, visuospatial ability and verbal memory. Eighty-nine per cent of the sample was correctly classified by discriminant analysis. Evaluating the ability of the obtained discriminant function to differentiate between groups of DAT and FTD in a new, clinically diagnosed sample of 38 cases yielded an overall success rate of 84%. The results suggest that cognitive tests may be helpful for differential diagnosis in the context of a neuropsychiatric examination.

Details

Authors
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Psychiatry
  • Geriatrics

Keywords

  • adult, aged, Alzheimer disease, article, autopsy, clinical article, clinical trial, cognition, dementia, depth perception, differential diagnosis, discriminant analysis, female, frontal lobe, human, male, neuropsychological test, task performance, verbal behavior, verbal memory
Original languageEnglish
Pages (from-to)635-642
JournalInternational Journal of Geriatric Psychiatry
Volume9
Issue number8
Publication statusPublished - 1994 Oct 29
Publication categoryResearch
Peer-reviewedYes