New directions of miniaturization within the proteomics research area

Research output: Contribution to journalReview article


title = "New directions of miniaturization within the proteomics research area",
abstract = "An overview of the current trends within protein expression profiling is given where multidimensional separation of both gel- and liquid-phase techniques linked to mass spectrometry is viewed as a major route in the global proteome mapping. A clear trend in these biochemical developments is the effort to sequence and identify low-abundant protein expressions where assay miniaturization and integrated sample processing plays a central role. Two areas of miniaturization within the proteomics field are addressed: (i) sample cleanup and enrichment, and (ii) silicon microstructure developments for protein chip microarrays.",
keywords = "proteomics, miniaturization, protein expression profiling, review",
author = "Gy{\"o}rgy Marko-Varga and Johan Nilsson and Thomas Laurell",
note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Biomedical Engineering (011200011), Analytical Chemistry (S/LTH) (011001004)",
year = "2003",
doi = "10.1002/elps.200305666",
language = "English",
volume = "24",
pages = "3521--3532",
journal = "Electrophoresis",
issn = "0173-0835",
publisher = "John Wiley & Sons",
number = "21",