Non-contact acoustic capture of platelet-derived microparticles from small plasma volumes

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceeding

Abstract

This paper presents the characterization and optimization of acoustic capture of platelet-derived microparticles (PMPs) from human plasma. The technique is compared to a standard preparation protocol using differential centrifugation on biobank samples from patients with ST-elevation myocardial infarction (STEMI). The main advantages of this new method are the capability of rapidly capturing microvesicles from small sample volumes and the potential to extract intact vesicles for downstream processing or handling.

Details

Authors
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Biomedical Laboratory Science/Technology

Keywords

  • Acoustic trapping, Acoustofluidics, Enrichment, Extracellular vesicles, Microparticles
Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages469-471
Number of pages3
ISBN (Electronic)9780979806483
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 2015 Oct 252015 Oct 29

Conference

Conference19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
CountryKorea, Republic of
CityGyeongju
Period2015/10/252015/10/29