Non-motor symptoms in patients with Parkinson's disease - correlations with inflammatory cytokines in serum.

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Abstract

Parkinson's Disease (PD) is the second most common neurodegenerative disorder of the central nervous system. Motor symptoms are the focus of pharmacotherapy, yet non-motor features of the disease (e.g. fatigue, mood disturbances, sleep disturbances and symptoms of anxiety) are both common and disabling for the patient. The pathophysiological mechanisms behind the non-motor symptoms in PD are yet to be untangled. The main objective of this study was to investigate associations between pro-inflammatory substances and non-motor symptoms in patients with PD.

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  • Neurology
Original languageEnglish
Article numbere47387
JournalPLoS ONE
Volume7
Issue number10
Publication statusPublished - 2012
Publication categoryResearch
Peer-reviewedYes

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