Novel form of ClpB/HSP100 protein in the cyanobacterium Synechococcus

Research output: Contribution to journalArticle


Synechococcus sp. strain PCC 7942 has a second clpB gene that encodes a 97-kDa protein with novel features. ClpBII is the first ClpB not induced by heat shock or other stresses; it is instead an essential, constitutive protein. ClpBII is unable to complement ClpBI function for acquired thermotolerance. No truncated ClpBII version is normally produced, unlike other bacterial forms, while ectopic synthesis of a putative truncated ClpBII dramatically decreased cell viability.


External organisations
  • Umeå University
Research areas and keywords


  • Adaptation, Biological, Bacterial Proteins/genetics, Cloning, Molecular, Cyanobacteria/genetics, Endopeptidase Clp, Gene Expression Regulation, Bacterial, Genes, Bacterial, Genes, Essential, Heat-Shock Proteins/genetics, Heat-Shock Response, Peptide Fragments/genetics, Sequence Analysis, DNA
Original languageEnglish
Pages (from-to)7392-6
Number of pages5
JournalJournal of Bacteriology
Issue number24
Publication statusPublished - 2001 Dec
Publication categoryResearch
Externally publishedYes