Novel metabolites from the roots of Cadaba natalensis

Research output: Contribution to journalArticle


From an extract of the roots of Cadaba natalensis Sond. the novel macrocyclic dibenzo-diazacyclododecanedione 1 was isolated together with (S)-2-ethyl-2-methyloxazolidin-5-one (2a). In addition, the five known compounds were obtained. Of these, (R)-5-ethyl-5-methyloxazolidin-2-one (3) is reported as a natural product for the first time. The structures of the isolated compounds were elucidated by analysis of the spectral data, 1D NMR (1H, 13C, and DEPT), 2D NMR (COSY, HMQC, HMBC, and NOESY), and HRESIMS, as well as by the comparison with previously reported data.


External organisations
  • Eduardo Mondlane University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Organic Chemistry
  • Botany


  • Cadaba natalensis, Diazacyclododecanedione, Isolation, Isoquiniline alkaloids, Oxazolidinone, Structure elucidation
Original languageEnglish
Pages (from-to)283-286
Number of pages4
JournalPhytochemistry Letters
Publication statusPublished - 2016 Jun 1
Publication categoryResearch

Related research output

Monjane, J., 2017 Nov, Lund: Lund University, Faculty of Science, Department of Chemistry, Centre for Analysis and Synthesis. 70 p.

Research output: ThesisDoctoral Thesis (compilation)

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