Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction
Research output: Contribution to journal › Article
Here we present a two-step diastereoselective methodology building on a multicomponent aza-Diels-Alder reaction. Using previously unexplored cyclic ketones, heterocyclic amines and cyclopentadiene derivatives, we obtained novel spiro-heterocyclic frameworks at the interphase between "drug-like" molecules and natural products.
|Journal||Organic and Biomolecular Chemistry|
|Publication status||Published - 2017 Sep 26|