Number of patients potentially eligible for proton therapy

Research output: Contribution to journalReview article

Abstract

A group of Swedish radiation oncologists and hospital physicists have estimated the number of patients in Sweden suitable for proton beam therapy in a facility where one of the principal aims is to facilitate randomized and other studies in which the advantage of protons can be shown and the magnitude of the differences compared with optimally administered conventional radiation treatment, also including intensity-modulated radiation therapy (IMRT) and brachytherapy, can be shown. The estimations have been based on current statistics of tumour incidence in Sweden, number of patients potentially eligible for radiation treatment, scientific support from clinical trials and model dose planning studies and knowledge of the dose-response relations of different tumours together with information on normal tissue complication rates. In Sweden, it is assessed that between 2200 and 2500 patients annually are eligible for proton beam therapy, and that for these patients the potential therapeutic benefit is so great as to justify the additional expense of proton therapy. This constitutes between 14- 15% of all irradiated patients annually.

Details

Authors
  • B Glimelius
  • Anders Ask
  • Göran Bjelkengren
  • T Bjork-Eriksson
  • E Blomquist
  • B Johansson
  • M Karlsson
  • B Zackrisson
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cancer and Oncology
Original languageEnglish
Pages (from-to)836-849
JournalActa Oncologica
Volume44
Issue number8
Publication statusPublished - 2005
Publication categoryResearch
Peer-reviewedYes