Obesity and cardiovascular risk: A call for action from the European Society of Hypertension Working Group of Obesity, Diabetes and the High-risk Patient and European Association for the Study of Obesity: Part A: Mechanisms of obesity induced hypertension, diabetes and dyslipidemia and practice guidelines for treatment

Research output: Contribution to journalReview article


Obesity is a key factor for cardiovascular diseases and complications. Obesity is associated with hypertension, dyslipidemia and type II diabetes, which are the major predictors of cardiovascular disease in the future. It predisposes for atrial fibrillation, heart failure, sudden cardiac death, renal disease and ischemic stroke that are the main causes of cardiovascular hospitalization and mortality. As obesity and the cardiovascular effects on the vessels and the heart start early in life, even from childhood, it is important for health policies to prevent obesity very early before the disease manifestation emerge. Key roles in the prevention are strategies to increase physical exercise, reduce body weight and to prevent or treat hypertension, lipids disorders and diabetes earlier and efficiently to prevent cardiovascular complications. Epidemiology and mechanisms of obesity-induced hypertension, diabetes and dyslipidemia will be reviewed and the role of lifestyle modification and treatment strategies in obesity will be updated and analyzed. The best treatment options for people with obesity, hypertension, diabetes and dyslipidemia will discussed.


  • Vasilios Kotsis
  • Jens Jordan
  • Dragan Micic
  • Nicholas Finer
  • Deborah R. Leitner
  • Hermann Toplak
  • Lale Tokgozoglu
  • Vasilios Athyros
  • Moses Elisaf
  • Theodosios D. Filippatos
  • Josep Redon
  • Pau Redon
  • Christina Antza
  • Konstantinos Tsioufis
  • Guido Grassi
  • Gino Seravalle
  • Antonio Coca
  • Cristina Sierra
  • Empar Lurbe
  • Stella Stabouli
  • Bojan Jelakovic
External organisations
  • Aristotle University of Thessaloniki
  • Hannover Medical School
  • University College London
  • Medical University of Graz
  • Hacettepe University
  • University of Ioannina
  • University of Crete
  • National and Kapodistrian University of Athens
  • Istituto Auxologico Italiano
  • University of Barcelona
  • Skåne University Hospital
  • Clinical Center of Serbia
  • University of Valencia
  • Carlos III Health Institute
  • IRCCS Multimedica
  • University of Milano-Bicocca
  • University Hospital Centre Zagreb
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cardiac and Cardiovascular Systems


  • cardiovascular risk, diabetes, dyslipidemia, guidelines, hypertension, obesity
Original languageEnglish
Pages (from-to)1427-1440
Number of pages14
JournalJournal of Hypertension
Issue number7
Publication statusPublished - 2018 Jul 1
Publication categoryResearch