One-pot three-component reaction for the synthesis of α-(aminoethyl)-α,β-enones

Research output: Contribution to journalArticle

Abstract

(equation presented) The synthesis of α-substituted α,β-enones by a new metal iodide-promoted one-pot three-component reaction involving commercially available cyclopropyl ketones, aldehydes, and secondary amines followed by base treatment is described.

Details

Authors
External organisations
  • ACADIA Pharmaceuticals Inc.
  • ACADIA Pharmaceuticals A/S
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Pharmaceutical Sciences
Original languageEnglish
Pages (from-to)4333-4336
JournalOrganic Letters
Volume4
Issue number24
Publication statusPublished - 2002 Nov 28
Publication categoryResearch
Peer-reviewedYes
Externally publishedYes